116. Structure of Cells, Tissues, and Organs. (10 units) Fa. Restrictions: D1 and DH1 students Lecture 7 hours. Laboratory 9 hours.
M. McMaster
This course focuses on structure of the human body, from cells to tissues to organs, with an emphasis on the oral cavity, and includes material on the mechanisms of disease. ( department: CELL&TISBI )
117. Infection and Host Response; Cell Physiology. (8 units) Wi. Prerequisites: Successful completion of Biomed 116 or consent of the instructor. Restrictions: D1 and DH1 students Lecture 6 hours. Laboratory 4 hours. Conference 1 hours.
S. Lowe
This course covers neuroanatomy (2 weeks) and microbiology-immunology (8 weeks). The neuroanatomy module covers structure and function of the brain, spinal cord, and cranial nerves, and the fundamentals of neurology. The microbiology-immunology module covers microorganisms, including bacteria, fungi, and viruses, fundamentals of infection and resistance, immunology, disinfection, sterilization, antimicrobial agents, indigenous oral flora, and applications of microbiology to dentistry. ( department: CELL&TISBI )
118. Organ Systems and Human Pathophysiology. (9.5 units) Sp. Prerequisites: Successful completion of Biomed 117 or consent of instructor. Restrictions: D1 and DH1 students Lecture 9 hours. Laboratory 1 hours. Conference 1 hours.
M. McMaster
This is the first quarter of a two quarter organ system-based course that combines basic science instruction in the disciplines of biochemistry, physiology, and pharmacology with instruction in pathology. Modules covered are Cell Physiology, Cardiovascular System, Pulmonary System, Renal System, and Neurology. ( department: CELL&TISBI )
126. Organ Systems and Human Pathophysiology. (6.5 units) Fa. Prerequisites: Successful completion of Biomed 118 or consent of instructor. Restrictions: D2 and DH2 students. Lecture 6 hours. Laboratory 2 hours.
M. McMaster
This course combines pathology and pharmacology. Within the pathology segment, mechanisms of disease are discussed with coverage of cell injury, immunopathology, inflammation, responses to infectious agents, repair, regeneration, genetic disorders, disturbances of cell growth, and neoplasia. Within the pharmacology segment, various classes of drugs are examined in regard to actions, absorption, fate, excretion, and toxicity. Applications to dentistry are emphasized. ( department: CELL&TISBI )
127. Oral Pathology. (2.5 units) Wi. Prerequisites: Successful completion of Biomed 126 or consent of instructor. Restrictions: D2, DH2, and ID3 students Lecture 2 hours. Independent study 2 hours.
J. Greenspan, J. Regezi, R. Jordan
Course correlates clinical oral pathology with histologic changes in tissues. Emphasis is placed on the microscopic and laboratory interpretation of cellular, tissue, and chemical alterations. Laboratory sessions concentrate on clinical presentation of oral diseases. ( department: CELL&TISBI )
186. Advanced projects in head and neck anatomy.. (1-3 units) § Fa, Wi, Sp. Prerequisites: Successful completion of BMS 116, 117, and 118. Restrictions: Enrollment requires permission of instructor. Laboratory 3-9 hours.
M. McMaster
For high achieving students who want more exposure to gross anatomy through cadaver dissection, and study of prosected specimens, texts, atlases and supplemental materials. Students perform advanced dissections to explore functional anatomy of the head/neck and develop prosections for teaching and board review. All elements of the course are under the supervision of the anatomy faculty and will enhance student knowledge and understanding of anatom. sciences. ( department: CELL&TISBI )
187. Laboratory Instruction in Gross Anatomy. (2 units) Fa. Prerequisites: Successful completion of BMS 116, 117, and 118. Restrictions: Enrollment requires permission of instructor. Laboratory 3 hours. Seminar 3 hours.
M. McMaster
This course provides advanced training for students interested in anatomical sciences. Upper-class students will TA first-year dental students in the gross anatomy laboratory and rotate with faculty answering questions and assisting with dissection and study of cadavers. It provides reinforcement of anatomic knowledge covered in the first year of dental education in preparation of the National Board Part 1. ( department: CELL&TISBI )
188. Basic sciences curriculum development. (1-3 units) Su, Fa, Wi, Sp. Prerequisites: Successful completion of BMS 116, 117, and 118. Restrictions: Enrollment requires persimission of insructor. Project 3-9 hours.
M. McMaster
Students will develop computer-based multimedia teaching tools working with basic science faculty. Projects will be incorporated into learning modules covering topics in the anatomy, histology, and/or neuroscience that will be applied in teaching and reviewing basic sciences for dental students. ( department: CELL&TISBI )
198. Supervised Study. (1-5 units) § Fa, Wi, Sp. Prerequisites: None. Library 3-15 hours.
W. Weiss
Library research and directed reading under supervision of a member of the faculty.
211. Human Evolution and Population Genetics. (3 units) § Wi. Prerequisites: BMS 255 or approval from instructor. Restrictions: Graduate student or instructor approval. Lecture 3 hours.
J. Wall
This course covers the basics of population and evolutionary genetics, including models of sequence evolution, genetic diversity within and between species, natural selection and speciation. We will also discuss the relevance of population genetics for understanding the genetic basis of complex and Mendelian diseases. ( department: EPID & BIO )
214. Ethics and the Responsible Conduct of Research. (2 units) § Wi, Sp. Prerequisites: None. Restrictions: None. Lecture 4 hours.
H. Bernstein, S. Baraban
This course will cover topics related to the responsible conduct of research such as conflicts of interest, responsible authorship, policies regarding the use of human and animal subjects, handling misconduct, proper data management, research funding rules and procedures. Students will review and present case studies for class discussion.
215. Laboratory Rotation. (3-5 units) § Fa, Wi, Sp. Laboratory 3-15 hours. Project 10 hours.
Staff
Research experience in the laboratory of Biomedical Sciences faculty members.
220. Basic and Clinical Aspects of Stem Cell Biology. (3 units) § Sp. Prerequisites: None. Restrictions: Class size limited to 40. Lecture 3 hours.
A. Kriegstein, K. Shannon
This course provides an overview of stem cell biology that integrates a description of basic concepts and technologies. Emphasis is on using stem cells to treat common human diseases such as diabetes, neurodegenerative disorders, and cancer and practical limitations that must be overcome to achieve the goal of widespread therapeutic use.
225A. Tissue & Organ Biology. (3 units) § Wi. Prerequisites: None. Restrictions: Admission to UCSF graduate program or permission of instructor. Lecture 3 hours.
B. Black, C. Vaisse, D. Pearce, H. Ingraham, J. Helms, M. Hebrok, M. German, P. Chuang, R. Farese, S. Fisher
An integrative course emphasizing frontiers in cell and molecular biology of human tissue and organ systems. It is intended to provide a foundation in human anatomy, histology, immunology, physiology and pathobiology for graduate students. Rather than a comprehensive course, selected topics will be discussed in depth. The emphasis may shift each year, depending on which topics are relevant and timely.
225B. Tissue and Organ Biology. (3 units) § Sp. Prerequisites: None. Restrictions: Admission to UCSF Graduate Program or permission of instructor. Lecture: 2.5; Lab: .5 3 hours.
M. German
An integrative course emphasizing frontiers in cell and molecular biology of human tissue and organ systems. It is intended to provide a foundation in human anatomy, histology, immunology, physiology and pathobiology for graduate students. Rather than a comprehensive course, selected topics will be discussed in depth. The emphasis may shift each year, depending on which topics are relevant and timely.
250. Research. (1-8 units) § Su, Fa, Wi, Sp. Prerequisites: Consent of instructor, Lab variable,.
Staff
255. Basic Genetics & Genomics. (4 units) § Wi. Lecture 4 hours. Laboratory 0-1 hours. paper 0-1 hours.
A. Balmain, C. Vaisse, C. Largman, D. Toczyski, J. Gray, J. Li, L. Criswell, L. Bull, N. Killeen, R. Andino, R. Reijo Pera
The scope of this graduate level course in genetics is to convey an understanding of basic genomics and molecular genetics, of the use of genetic animal model systems and of the analytical principles of simple and complex human genetic traits. ( department: PHYSIOLOGY )
260. Cell Biology. (4 units) § Fa. Lecture 3 hours. Conference 1 hours.
D. Barber, G. Evan, H. Bourne, J. Cyster, K. Mostov, L. Coussens, Z. Werb
The scope of this course is to convey an understanding of the function and organizatiion of molecules and organelles inside and outside the cell and how these are used to construct a multicellular tissue and organ. The course will concentrate on questions related to how cells function, includig how they grow, divide and die, and how thry moe, secrete and communicate. ( department: PHYSIOLOGY )
265. Macromolecular Structure & Function. (3 units) § Sp. Prerequisites: None. Restrictions: None Lecture 3 hours. Workshop 2 hours.
J. McKerrow, S. Fisher
This course introduces graduate students to the basic biochemistry and analysis of proteins and nucleic acid, and is tailored directly to the thematic interests of BMS students. It covers amino acid and peptide chemistry, protein folding, protein structural analysis, enzymology, nucleic acid structure, protein nucleic acid interactions, proteomics, and structure/based drug design.
301. Science Writing. (1 units) § Fa, Wi, Sp. Prerequisites: Completion of the first year of graduate school. Restrictions: Maximum of 16 students. Workshop 4 hours.
M. Zeiger
This course introduces the principles for basic techniques of clear scientific writing, such as word choice, sentence structure and paragraph structure, and then applies these techniques to one section of a scientific paper (the introduction).
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