111. Biopharmaceutics. (3.5 units) Fa. Prerequisites: First-year standing in School of Pharmacy. Lecture 3 hours. Workshop 2 hours.
X. Chen
This course is about how drug dosage forms can be used as drug delivery systems. It will explain routes of administration, pharmaceutics, biopharmaceutics, bioavailability, bioequivalency, rate and extent of availability, onset and duration of effect, getting to the site of absorption, dissolution, disintegration, first-pass effect, passive diffusion and active transport. ( department: BIO THERAP )
112. Biostatistics. (2.5 units) Fa. Lecture 2 hours. Conference 1 hours.
B. Jersky
This course is an introductory course in biostatistics covering topics such as elementary probability theory, hypothesis testing, analysis of variance, t-tests, Z- and chi-square tests, regression and correlation, nonparametric methods, estimation and confidence intervals, and computer-aided solutions. ( department: BIO THERAP )
113. Drug Delivery Systems. (2 units) Sp. Prerequisites: Concurrent enrollment in BPS 114 and 115 or permission of instructor. Restrictions: None. Lecture 2 hours.
A. Sali, F. Szoka, T. Kortemme
This course will introduce pharmacy students to the various routes and delivery systems for administration of drugs. ( department: BIO THERAP )
114. Bioinformatics. (2 units) Sp. Prerequisites: Concurrent enrollment in BPS 113 and 115 or permission of instructor.
. Restrictions: None. Laboratory 3 hours.
A. Sali, P. Babbitt, T. Kortemme
This course is an introduction to bioinformatics and other informatics resources for pharmacy students. The goal is to familiarize students with primary informatics resources for research and patient information and to introduce them to fundamentals of human health from the perspective of the human genome and related projects. ( department: BIO THERAP )
115. Genetics and Pharmacogenetics. (2 units) Sp. Prerequisites: Concurrent enrollment in BPS 113 and 114 or permission of instructor. Restrictions: None. Lecture 2 hours. Conference 1 hours.
D. Kroetz, E. Burchard, S. Guo
This is a course to introduce pharmacy students to the basic principles of genetics and apply them to pharmacogenetics. ( department: BIO THERAP )
121. Pharmacokinetics. (4 units) Fa. Prerequisites: Biopharmaceutical Sciences 111 and 113. Lecture 3 hours. Conference 2 hours.
D. Kroetz
An introduction to the principles of pharmacokinetics with the goal of producing a student pharmacist who is capable of using the fundamentals proficiently. ( department: BIO THERAP )
122. Pharmacokinetics. (3 units) Wi. Prerequisites: Biopharmaceutical Sciences 121. Lecture 2 hours. Conference 2 hours.
B. Hoener
A continuation of Biopharmaceutical Sciences 121 in which student pharmacists will learn the sources of variability in the body's handling of drugs and how these influence kinetics and dosing of drugs. ( department: BIO THERAP )
132. Drug Development Sciences. (2-3 units) Wi. Lecture 4 hours. Project 4 hours.
D. Kroetz
This course focuses on the areas of drug metabolism, delivery and transport as they pertain to the area of new drug design and development. ( department: BIO THERAP )
133. Pharmacokinetics in Drug Development. (3 units) Sp. Prerequisites: Satisfactory completion of BPS 122. Lecture 2 hours. Project 2 hours.
F. Aweeka
The course will provide advanced training in pharmacokinetics with a focus on the issues involved with drug development. ( department: BIO THERAP )
134. Research Design & Statistics in Drug Development. (3 units) Wi. Prerequisites: None. Restrictions: This course is required for students in the Pharmaceutical Sciences Pathway, but is open to all students as an elective if space permits. Lecture 2 hours. Project 3 hours.
N. Sambol
This course covers detailed aspects of optimizing research design for clinical and basic research. The material presented builds on the content covered in the Study Design Course of the first year curriculum. Design strategies for varying types of research as well as skills for critical evaluation of research studies and literature will be the primary focus. In addition, the ethics of using animals and humans will be discussed. ( department: BIO THERAP )
135. Principles of Pharmacogenomics. (3 units) Sp. Prerequisites: None. Restrictions: None. Lecture 2 hours. Conference 2 hours.
K. Giacomini
This course provides students with a comprehensive overview of the genetic basis for differences in drug response. Genetic variability in drug receptors, transporters and enzymes as well as regulatory proteins involved in promoting and inhibiting transcription and translation will be discussed. The course also covers toxicogenetics and an introduction to computational genomics. ( department: BIO THERAP )
165. Pharmaceutical Sci. Pathway Project: Biopharmaceutical Sciences. (4-10 units) Su, Fa, Wi, Sp, SS1, SS2, SS3. Prerequisites: Successful completion of BIOPHRM SC 134 Research Design. Restrictions: Pharmacy students must have completed their 3rd year of professional courses or consent of instructor. Independent Study 12-30 hours.
S. Kahl
This course is designed to introduce students to research. Students will work closely with a member of the faculty and will focus on a specific project. Students will will write a grant for protocol summarizing the work planned, carry out hands-on aspects of the research, analyze results and present findings. ( department: BIO THERAP )
198. Supervised Study in Biopharmaceutical Sciences. (1-5 units) Fa, Wi, Sp, SS1, SS2, SS3. Laboratory 2 hours. Seminar 1 hours.
Staff
Library research and directed reading under supervision of a member of the faculty with the approval of the chairperson of the department. ( department: BIO THERAP )
199. Laboratory Project in Biopharmaceutical Sciences. (1-5 units) Fa, Wi, Sp, SS1, SS2, SS3. Laboratory 2 hours. Seminar 1 hours.
Staff
A laboratory research project under direction of a member of the faculty with the approval of the chairperson of the department. ( department: BIO THERAP )
272A. Advanced Drug Delivery: Controlled and Targeted Drug Delivery. (2 units) § Wi. Prerequisites: Chemistry 241 or equivalent. Laboratory 0-6 hours. Project 0-1 hours.
F. Szoka
The focus of this course is on the chemical, biophysical and biological factors that impact on targeted and controlled drug delivery systems. There is a particular emphasis on colloidal systems and systems that provide a regulated controlled release. ( department: PHARMGENOM )
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