170. Group Studies Course. (1-4 units) Fa, Wi, Sp. Prerequisites: Consent of instructor. Lecture 1-4 hours.
Staff
Group studies in selected topics in chemistry. ( department: PHARM CHEM )
203. Synthetic Organic Chemistry. (3 units) § Sp. Prerequisites: undergraduate organic chemistry. Lecture 3 hours.
T. Scanlan
The course covers modern methods in synthetic organic chemistry. Lecture material focuses on new reagents, synthetic strategies, and functional group conversions. Applications of organic synthesis to biological research problems are also highlighted. ( department: PHARM CHEM )
219. Special Topics in Basic and Translational Chemical Biology. (3 units) § Fa, Wi, Sp. Prerequisites: None. Completion of 1st year curriculum in Chemistry and Chemical Biology or another experimental biology graduate program is helpful, but not essential. Restrictions: Chemistry and Chemical Biology graduate students, other graduate and professional students with interest in Chemical Biology. Permission from instructor is required. Lecture 1 hours. Conference 2 hours. Ind. Study: 3 3 hours.
Staff
Each course offering will focus on the literature of a current area of Chemical Biology research. Students will be expected to read assigned papers critically before class and to present and discuss papers in class. Students will also be expected to write and present a brief research proposal based upon their reading. Topics in synthetic chemistry, NMR Practical, and Mass Spectroscopy will be covered in separate course offerings. ( department: PHARM CHEM )
241. Molecular Thermodynamics. (5 units) § Fa. Prerequisites: none. Lecture 5 hours.
K. Dill
This is a course on molecular thermodynamics and statistical mechanics. It covers the concepts of entropy, enthalpy, heat capacity, free energy, ligand binding, solvation, the properties of water, the hydrophobic effect, solution electrostatics, adsorption, and physical and chemical kinetics. ( department: PHARM CHEM )
242. Physical Organic Chemistry. (3 units) § Wi. Prerequisites: None. Restrictions: Graduate standing or permission of the instructor. Lecture 2 hours. Laboratory 1 hours.
P. England
Fundamentals of physical organic chemistry with an emphasis on the principles and practices of modern spectroscopy applied to structure determination of small molecules. ( department: PHARM CHEM )
243. Chemical Biology. (5 units) § Wi. Lecture 5 hours.
C. Craik
Basics of chemical biology with a particular emphasis on understanding and manipulating molecular mechanisms of complex biochemical phenomena. Lectures will address macromolecular structure, function, mechanisms, synthesis and metabolism applications. ( department: PHARM CHEM )
244. Reaction Mechanisms. (3 units) § Wi. Prerequisites: Graduate standing or consent of instructor. Lecture 3 hours.
K. Shokat
This course is designed to develop the student's knowledge of organic mechanisms. Thisinteractive course involves some lectures, but enforces student learning through intensive arrow pushing sessions with students at the board. Topics include electrocyclic reactions, Woodward-Hoffman rules, sigmatropic reactions, migration reactions, neighboring group effects, carbanions and free radicals, carbenoids, nitrenes, six-membered heterocyclic rings, five-membered heteroclyclic rings. ( department: PHARM CHEM )
264. Advanced Statistical Mechanics & Molecular Mechanics. (2 units) § Sp. Prerequisites: Chemistry 260 or consent of instructor. Lecture 2 hours.
K. Dill
Advanced aspects of statistical mechanics and molecular mechanics; topics covered vary from year to year. ( department: PHARM CHEM )
297. Chemistry and Chemical Biology Journal Club. (1 units) § Su, Fa, Wi, Sp, SS1, SS2, SS3. Prerequisites: None. Restrictions: None. Seminar 3 hours.
C. Craik
Readings and conferences based on topics in chemistry and chemical biology. Students are required to present in journal club, once in the first year and once in the second year. This experience will assist students in perfecting communication skills of the scientific literature. ( department: PHARM CHEM )
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