Course Listing for Biomedical Sciences

116  Structure of Cells, Tissues, and Organs  (10 units)   Fall

Instructor(s): M. McMaster

Restrictions: D1 and DH1 students       Activities: Lecture, Laboratory

This course focuses on structure of the human body, from cells to tissues to organs, with an emphasis on the oral cavity, and includes material on the mechanisms of disease.(CELL&TISBI)

117  Infection and Host Response; Cell Physiology  (8 units)   Winter

Instructor(s): E. Joyce, P. Sargent       Prerequisite(s): Successful completion of Biomed 116 or consent of the instructor

Restrictions: D1 and DH1 students       Activities: Lecture, Conference, Laboratory

This course covers neuroanatomy (2 weeks) and microbiology-immunology (8 weeks). The neuroanatomy module covers structure and function of the brain, spinal cord, and cranial nerves, and the fundamentals of neurology. The microbiology-immunology module covers microorganisms, including bacteria, fungi, and viruses, fundamentals of infection and resistance, immunology, disinfection, sterilization, antimicrobial agents, indigenous oral flora, and applications of microbiology to dentistry.(CELL BIOL)

118  Organ Systems and Human Pathophysiology  (9.5 units)   Spring

Instructor(s): M. McMaster       Prerequisite(s): Successful completion of Biomed 117 or consent of instructor.

Restrictions: D1 and DH1 students       Activities: Lecture, Conference, Laboratory

This is the first quarter of a two quarter organ system-based course that combines basic science instruction in the disciplines of biochemistry, physiology, and pharmacology with instruction in pathology. Modules covered are Cell Physiology, Cardiovascular System, Pulmonary System, Renal System, and Neurology.(CELL&TISBI)

126  Organ Systems and Human Pathophysiology  (6.5 units)   Fall

Instructor(s): M. McMaster       Prerequisite(s): Successful completion of Biomed 118 or consent of instructor.

Restrictions: D2 and DH2 students.       Activities: Lecture, Laboratory

This course combines pathology and pharmacology. Within the pathology segment, mechanisms of disease are discussed with coverage of cell injury, immunopathology, inflammation, responses to infectious agents, repair, regeneration, genetic disorders, disturbances of cell growth, and neoplasia. Within the pharmacology segment, various classes of drugs are examined in regard to actions, absorption, fate, excretion, and toxicity. Applications to dentistry are emphasized.(CELL&TISBI)

127  Oral Pathology  (2.5 units)   Winter

Instructor(s): R. Jordan, J. Greenspan, J. Regezi       Prerequisite(s): Successful completion of Biomed 126 or consent of instructor

Restrictions: D2, DH2, and ID3 students       Activities: Lecture, Independent Study

Course correlates clinical oral pathology with histologic changes in tissues. Emphasis is placed on the microscopic and laboratory interpretation of cellular, tissue, and chemical alterations. Laboratory sessions concentrate on clinical presentation of oral diseases.(CELL&TISBI)

186  Advanced projects in head and neck anatomy.  (1 - 3 units)   §   Fall, Winter, Spring

Instructor(s): M. McMaster       Prerequisite(s): Successful completion of BMS 116, 117, and 118.

Restrictions: Enrollment requires permission of instructor.       Activities: Laboratory

For high achieving students who want more exposure to gross anatomy through cadaver dissection, and study of prosected specimens, texts, atlases and supplemental materials. Students perform advanced dissections to explore functional anatomy of the head/neck and develop prosections for teaching and board review. All elements of the course are under the supervision of the anatomy faculty and will enhance student knowledge and understanding of anatom. sciences.(CELL&TISBI)

187  Laboratory Instruction in Gross Anatomy  (2 units)   Fall

Instructor(s): M. McMaster       Prerequisite(s): Successful completion of BMS 116, 117, and 118.

Restrictions: Enrollment requires permission of instructor.       Activities: Seminar, Laboratory

This course provides advanced training for students interested in anatomical sciences. Upper-class students will TA first-year dental students in the gross anatomy laboratory and rotate with faculty answering questions and assisting with dissection and study of cadavers. It provides reinforcement of anatomic knowledge covered in the first year of dental education in preparation of the National Board Part 1.(CELL&TISBI)

188  Basic sciences curriculum development  (1 - 3 units)   Fall, Winter, Spring, Summer

Instructor(s): M. McMaster       Prerequisite(s): Successful completion of BMS 116, 117, and 118.

Restrictions: Enrollment requires persimission of insructor.       Activities: Project

Students will develop computer-based multimedia teaching tools working with basic science faculty. Projects will be incorporated into learning modules covering topics in the anatomy, histology, and/or neuroscience that will be applied in teaching and reviewing basic sciences for dental students.(CELL&TISBI)

198  Supervised Study  (1 - 5 units)   §   Fall, Winter, Spring

Instructor(s): B. Stohr       Prerequisite(s): None

Library research and directed reading under supervision of a member of the faculty.(BMS PROG)

211  Human Evolution and Population Genetics  (3 units)   §   Winter

Instructor(s): J. Wall       Prerequisite(s): BMS 255 or approval from instructor.

Restrictions: Graduate student or instructor approval.       Activities: Lecture

This course covers the basics of population and evolutionary genetics, including models of sequence evolution, genetic diversity within and between species, natural selection and speciation. We will also discuss the relevance of population genetics for understanding the genetic basis of complex and Mendelian diseases.(EPID & BIO)

214  Ethics and the Responsible Conduct of Research  (2 units)   §   Spring

Instructor(s): B. Conklin       Prerequisite(s): None.

Restrictions: None.       Activities: Lecture

This course will cover topics related to the responsible conduct of research such as conflicts of interest, responsible authorship, policies regarding the use of human and animal subjects, handling misconduct, proper data management, research funding rules and procedures. Students will review and present case studies for class discussion.(BMS PROG)

215  Laboratory Rotation  (3 - 5 units)   §   Fall, Winter, Spring

Instructor(s): Staff

Activities: Laboratory, Project

Research experience in the laboratory of Biomedical Sciences faculty members.(BIOMED SCI)

225A  Human Disease: Technologies & Biomedical Applications  (1.5 units)   §   Fall

Instructor(s): S. Kogan, M. German       Prerequisite(s): None.

Restrictions: Admission to UCSF Graduate Program or permission of instructor.       Activities: Lecture, Seminar

Integrative course emphasizing technologies for cell & molecular biology and the application of these methods to understand human disease. Intended to provide a foundation for graduate students in methods used to understand human cells, tissues, & organs, and to illustrate how these methods illuminate physiology and pathobiology. Rather than a comprehensive course, selected topics will be discussed in depth. The emphasis may shift each year, depending upon which topics are relevant and timely.(PATHOLOGY)

225B  Tissue and Organ Biology  (3 units)   §   Winter

Instructor(s): D. Gould       Prerequisite(s): None.

Restrictions: Admission to UCSF Graduate Program or permission of instructor.       Activities: Lecture

An integrative course emphasizing frontiers in cell and molecular biology of human tissue and organ systems. It is intended to provide a foundation in human anatomy, histology, immunology, physiology and pathobiology for graduate students. Rather than a comprehensive course, selected topics will be discussed in depth. The emphasis may shift each year, depending on which topics are relevant and timely.(BMS PROG)

230  Advanced Topics in Cancer Research  (4 units)   §   Fall

Instructor(s): M. McMahon, J. Debnath       Prerequisite(s): None.

Restrictions: None.       Activities: Lecture, Seminar

Lectures will guide understanding of the epidemiologic, molecular genetic, cell and pathobiological aspects of cancer focusing on 1) regulatory and effector mechanisms, 2) the cells constituting tumor microenvironments, and 3) relationships between basic biomedical research and their clinical applications. In Advanced Topics, students will present literature reports based on Lecture content supported by a Faculty Discussion leader who will pose an interesting/controversial spin on the topic.(BMS PROG)

250  Research  (1 - 8 units)   §   Fall, Winter, Spring, Summer

Instructor(s): Staff       Prerequisite(s): Consent of instructor, Lab variable.

(BIOMED SCI)

255  Basic Genetics & Genomics  (4 units)   §   Winter

Instructor(s): C. Vaisse, R. Andino, A. Balmain, L. Bull, L. Criswell, J. Gray, N. Killeen, C. Largman, J. Li, D. Toczyski

Activities: Lecture, Laboratory

The scope of this graduate level course in genetics is to convey an understanding of basic genomics and molecular genetics, of the use of genetic animal model systems and of the analytical principles of simple and complex human genetic traits.(PHYSIOLOGY)

260  Cell Biology  (4 units)   §   Fall

Instructor(s): D. Barber, K. Mostov, G. Evan, V. Weaver

Activities: Lecture, Conference

The scope of this course is to convey an understanding of the function and organizatiion of molecules and organelles inside and outside the cell and how these are used to construct a multicellular tissue and organ. The course will concentrate on questions related to how cells function, including how they grow, divide and die, and how they move, secrete and communicate.(BMS PROG)

270  Special Topics in Biomedical Sciences  (3 units)   §   Fall, Winter, Spring

Instructor(s): Staff       Prerequisite(s): None. Completion of first-year curriculum in Biomedical Sciences or another experimental biology graduate program is helpful but not essential.

Restrictions: Biomedical Sciences graduate students and other graduate and professional students with interest in Biomedical Sciences. Permission from instructor is required.       Activities: Lecture, Conference, Independent Study

Each course offering will focus on literature of a current important area of Biomedical Sciences research. Students will be expected to read assigned papers critically before class and to present and discuss papers in class. Students will also be expected to write and present a brief research proposal based upon their reading.(BIOMED SCI)

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