Course Listing for Biomedical Sciences


116 Structure of Cells, Tissues, and Organs (10 units)

Fall
Instructor(s):M. McMaster
Restrictions:D1 and DH1 students Activities: Lecture, Laboratory
This course focuses on structure of the human body, from cells to tissues to organs, with an emphasis on the oral cavity, and includes material on the mechanisms of disease. (CELL&TISBI)


117 Infection and Host Response; Cell Physiology (8 units)

Winter
Instructor(s):E. Joyce, P. Sargent Prerequisite(s): Successful completion of Biomed 116 or consent of the instructor
Restrictions:D1 and DH1 students Activities: Lecture, Laboratory, Conference
This course covers neuroanatomy (2 weeks) and microbiology-immunology (8 weeks). The neuroanatomy module covers structure and function of the brain, spinal cord, and cranial nerves, and the fundamentals of neurology. The microbiology-immunology module covers microorganisms, including bacteria, fungi, and viruses, fundamentals of infection and resistance, immunology, disinfection, sterilization, antimicrobial agents, indigenous oral flora, and applications of microbiology to dentistry. (CELL BIOL)


118 Organ Systems and Human Pathophysiology (9.5 units)

Spring
Instructor(s):M. McMaster Prerequisite(s): Successful completion of Biomed 117 or consent of instructor.
Restrictions:D1 and DH1 students Activities: Lecture, Laboratory, Conference
This is the first quarter of a two quarter organ system-based course that combines basic science instruction in the disciplines of biochemistry, physiology, and pharmacology with instruction in pathology. Modules covered are Cell Physiology, Cardiovascular System, Pulmonary System, Renal System, and Neurology. (CELL&TISBI)


126 Organ Systems and Human Pathophysiology (6.5 units)

Fall
Instructor(s):M. McMaster Prerequisite(s): Successful completion of Biomed 118 or consent of instructor.
Restrictions:D2 and DH2 students. Activities: Lecture, Laboratory
This course combines pathology and pharmacology. Within the pathology segment, mechanisms of disease are discussed with coverage of cell injury, immunopathology, inflammation, responses to infectious agents, repair, regeneration, genetic disorders, disturbances of cell growth, and neoplasia. Within the pharmacology segment, various classes of drugs are examined in regard to actions, absorption, fate, excretion, and toxicity. Applications to dentistry are emphasized. (CELL&TISBI)


127 Oral Pathology (2.5 units)

Winter
Instructor(s):R. Jordan, J. Greenspan, J. Regezi Prerequisite(s): Successful completion of Biomed 126 or consent of instructor
Restrictions:D2, DH2, and ID3 students Activities: Lecture, Independent Study
Course correlates clinical oral pathology with histologic changes in tissues. Emphasis is placed on the microscopic and laboratory interpretation of cellular, tissue, and chemical alterations. Laboratory sessions concentrate on clinical presentation of oral diseases. (CELL&TISBI)


186 Advanced projects in head and neck anatomy. (1 - 3 units)

§

Fall, Winter, Spring
Instructor(s):M. McMaster Prerequisite(s): Successful completion of BMS 116, 117, and 118.
Restrictions:Enrollment requires permission of instructor. Activities: Laboratory
For high achieving students who want more exposure to gross anatomy through cadaver dissection, and study of prosected specimens, texts, atlases and supplemental materials. Students perform advanced dissections to explore functional anatomy of the head/neck and develop prosections for teaching and board review. All elements of the course are under the supervision of the anatomy faculty and will enhance student knowledge and understanding of anatom. sciences. (CELL&TISBI)


187 Laboratory Instruction in Gross Anatomy (2 units)

Fall
Instructor(s):M. McMaster Prerequisite(s): Successful completion of BMS 116, 117, and 118.
Restrictions:Enrollment requires permission of instructor. Activities: Laboratory, Seminar
This course provides advanced training for students interested in anatomical sciences. Upper-class students will TA first-year dental students in the gross anatomy laboratory and rotate with faculty answering questions and assisting with dissection and study of cadavers. It provides reinforcement of anatomic knowledge covered in the first year of dental education in preparation of the National Board Part 1. (CELL&TISBI)


188 Basic sciences curriculum development (1 - 3 units)

Fall, Winter, Spring, Summer
Instructor(s):M. McMaster Prerequisite(s): Successful completion of BMS 116, 117, and 118.
Restrictions:Enrollment requires persimission of insructor. Activities: Project
Students will develop computer-based multimedia teaching tools working with basic science faculty. Projects will be incorporated into learning modules covering topics in the anatomy, histology, and/or neuroscience that will be applied in teaching and reviewing basic sciences for dental students. (CELL&TISBI)


198 Supervised Study (1 - 5 units)

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Fall, Winter, Spring
Instructor(s):D. Gould Prerequisite(s): None
Activities: Library
Library research and directed reading under supervision of a member of the faculty. (BIOMED SCI)


211 Human Evolution and Population Genetics (3 units)

§

Winter
Instructor(s):J. Wall Prerequisite(s): BMS 255 or approval from instructor.
Restrictions:Graduate student or instructor approval. Activities: Lecture
This course covers the basics of population and evolutionary genetics, including models of sequence evolution, genetic diversity within and between species, natural selection and speciation. We will also discuss the relevance of population genetics for understanding the genetic basis of complex and Mendelian diseases. (EPID & BIO)


214 Ethics and the Responsible Conduct of Research (2 units)

§

Spring
Instructor(s):H. Bernstein Prerequisite(s): None.
Restrictions:None. Activities: Lecture
This course will cover topics related to the responsible conduct of research such as conflicts of interest, responsible authorship, policies regarding the use of human and animal subjects, handling misconduct, proper data management, research funding rules and procedures. Students will review and present case studies for class discussion. (BMS PROG)


215 Laboratory Rotation (3 - 5 units)

§

Fall, Winter, Spring
Instructor(s):Staff
Activities: Laboratory, Project
Research experience in the laboratory of Biomedical Sciences faculty members. (BIOMED SCI)


225A Human Disease: Technologies & Biomedical Applications (1.5 units)

§

Fall
Instructor(s):S. Kogan, M. German Prerequisite(s): None.
Restrictions:Admission to UCSF Graduate Program or permission of instructor. Activities: Lecture, Seminar
Integrative course emphasizing technologies for cell & molecular biology and the application of these methods to understand human disease. Intended to provide a foundation for graduate students in methods used to understand human cells, tissues, & organs, and to illustrate how these methods illuminate physiology and pathobiology. Rather than a comprehensive course, selected topics will be discussed in depth. The emphasis may shift each year, depending upon which topics are relevant and timely. (PATHOLOGY)


225B Tissue and Organ Biology (3 units)

§

Winter
Instructor(s):A. Wynshaw-Boris Prerequisite(s): None.
Restrictions:Admission to UCSF Graduate Program or permission of instructor. Activities: Lecture
An integrative course emphasizing frontiers in cell and molecular biology of human tissue and organ systems. It is intended to provide a foundation in human anatomy, histology, immunology, physiology and pathobiology for graduate students. Rather than a comprehensive course, selected topics will be discussed in depth. The emphasis may shift each year, depending on which topics are relevant and timely. (BIOMED SCI)


230 Advanced Topics in Cancer Research (4 units)

§

Fall
Instructor(s):M. McMahon, J. Debnath Prerequisite(s): None.
Restrictions:None. Activities: Lecture, Seminar
Lectures will guide understanding of the epidemiologic, molecular genetic, cell and pathobiological aspects of cancer focusing on 1) regulatory and effector mechanisms, 2) the cells constituting tumor microenvironments, and 3) relationships between basic biomedical research and their clinical applications. In Advanced Topics, students will present literature reports based on Lecture content supported by a Faculty Discussion leader who will pose an interesting/controversial spin on the topic. (BMS PROG)


250 Research (1 - 8 units)

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Fall, Winter, Spring, Summer
Instructor(s):Staff Prerequisite(s): Consent of instructor, Lab variable.
(BIOMED SCI)


255 Basic Genetics & Genomics (4 units)

§

Winter
Instructor(s):C. Vaisse, R. Andino, A. Balmain, L. Bull, L. Criswell, J. Gray, N. Killeen, C. Largman, J. Li, D. Toczyski
Activities: Lecture, Laboratory
The scope of this graduate level course in genetics is to convey an understanding of basic genomics and molecular genetics, of the use of genetic animal model systems and of the analytical principles of simple and complex human genetic traits. (PHYSIOLOGY)


260 Cell Biology (4 units)

§

Fall
Instructor(s):D. Barber, K. Mostov, G. Evan, V. Weaver
Activities: Lecture, Conference
The scope of this course is to convey an understanding of the function and organizatiion of molecules and organelles inside and outside the cell and how these are used to construct a multicellular tissue and organ. The course will concentrate on questions related to how cells function, including how they grow, divide and die, and how they move, secrete and communicate. (BMS PROG)


270 Special Topics in Biomedical Sciences (3 units)

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Fall, Winter, Spring
Instructor(s):Staff Prerequisite(s): None. Completion of first-year curriculum in Biomedical Sciences or another experimental biology graduate program is helpful but not essential.
Restrictions:Biomedical Sciences graduate students and other graduate and professional students with interest in Biomedical Sciences. Permission from instructor is required. Activities: Lecture, Conference, Independent Study
Each course offering will focus on literature of a current important area of Biomedical Sciences research. Students will be expected to read assigned papers critically before class and to present and discuss papers in class. Students will also be expected to write and present a brief research proposal based upon their reading. (BIOMED SCI)